Results 181 to 190 of about 8,067,684 (279)

An open-source JavaScript clinical neurophysiology library for education and clinical research. [PDF]

Clin Neurophysiol Pract
Lohi S, Julkunen P, Kälviäinen R, Mervaala E.   +3 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Why open source?

Cadernos de Saúde Pública, 2015
Marilia Sá Carvalho
doaj   +1 more source

Open-source framework for detecting bias and overfitting for large pathology images. [PDF]

PLoS One
Sildnes A, Shvetsov N, Tafavvoghi M, Tran VN, Møllersen K, Busund LR, Kilvær TK, Bongo LA.   +7 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

LipidLocator: an open source Shiny web application for spatial lipidomics. [PDF]

Bioinform Adv
Arora P, Isfort S, Kirschke N, Masoodi M, Mercader N.   +4 more
europepmc   +1 more source

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

GARDE-Chat: a scalable, open-source platform for building and deploying health chatbots. [PDF]

J Am Med Inform Assoc
Del Fiol G, Borsato E, Bradshaw RL, Bian J, Woodbury A, Gauchel C, Eilbeck KL, Maxwell W, Ellis K, Madeo AC, Schlechter C, Kukhareva PV, Allen CG, Kean M, Elkin EB, Sharaf R, Ahsan MD, Frey M, Davis-Rivera L, Kohlmann WK, Wetter DW, Kaphingst KA, Kawamoto K.   +22 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source