Results 251 to 260 of about 16,728,413 (378)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
opynfield: An Open-Source Python Package for the Analysis of Open Field Exploration Data. [PDF]
NeuroinformaticsMcMullen E +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets. [PDF]
Imaging Neurosci (Camb)Yasinzai MN, Mito R, Pedersen M.
europepmc +1 more source
Open-Source Selective Laser Sintering (OpenSLS) of Nylon and Biocompatible Polycaprolactone
, 2016 Ian S. Kinstlinger +7 more
openalex +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source