Results 131 to 140 of about 192,525 (251)

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

Advanced Healthcare Materials, EarlyView.
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale, Nguyen Van Duc Long, Philip M. Williams, Jens Hauslage, Volker Hessel   +4 more
wiley   +1 more source

Maturity, Safety, and Equity of AI-Enabled Systems and Triage in Integrated Primary Care. [PDF]

J Med Internet Res
Liaw ST.
europepmc   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

A Novel Drug‐Loaded Porous Parylene Electrode for Targeted Anti‐Inflammatory Therapy and Hearing Preservation in Cochlear Implantation

Advanced Healthcare Materials, EarlyView.
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang, Ying‐Chang Lu, Yu‐Ming Chang, Yen‐Hui Chan, Hong‐Yu Yan, Yi‐Shan Lee, Pei‐Hsuan Lin, Cheng‐Yu Hsieh, Chuan‐Jen Hsu, Tien‐Chen Liu, Hsien‐Yeh Chen, Chen‐Chi Wu   +11 more
wiley   +1 more source

Analysis of the motivations, impacts, and countermeasures of the global open-source strategy for large models

大数据
Recently, the open-source routes of Alibaba and DeepSeek have sparked a global open-source wave. The European Union clearly signaled its support for the development of open source at the Paris AI Action Summit. Google and Microsoft have successively open-
TAN Jun, CHENG Ying, LIU Zhipeng
doaj  

Open-Source Large Language Models and AI Health Equity: A Health Service Triangle Model Perspective. [PDF]

J Med Internet Res
Wu S, Zou W, Tu J, Wang C, Jin C, Liao J, Tang KC, Liu N, Hao C.   +8 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Plagiarism in the Age of Generative Artificial Intelligence: The advent of generative artificial intelligence (GenAI) tools is challenging the scientific community's understanding of the meaning and significance of plagiarism. A new definition of research misconduct is needed that specifically addresses the use of GenAI writing tools. [PDF]

Nat Mach Intell
Resnik D, Hosseini M.
europepmc   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, EarlyView.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source

Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open-Source Artificial Intelligence Model SEE-AI. [PDF]

DEN Open
Miyazono S, Umeno J, Nagasue T, Saiki T, Kaku H, Torisu T, Yokote A, Kawasaki K, Ihara Y, Matsuno Y, Imazu N, Moriyama T, Mohamed AN, Hirakawa K, Yamagata H, Okamoto Y, Kurahara K, Yada S, Harada A, Ago T.   +19 more
europepmc   +1 more source