Results 91 to 100 of about 1,180,256 (306)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
ELFO: A Python Package for Emission Line Fitting Optimization in Integral Field Spectroscopy Data
The Astronomical JournalIntegral field spectroscopy (IFS) provides spatially resolved spectra, enabling detailed studies that address the physical and kinematic properties of the interstellar medium.
Hui Guo +6 more
doaj +1 more source
Open Source Software: The New Intellectual Property Paradigm [PDF]
Open source methods for creating software rely on developers who voluntarily reveal code in the expectation that other developers will reciprocate. Open source incentives are distinct from earlier uses of intellectual property, leading to different types
Stephen M. Maurer, Suzanne Scotchmer
core
An Empirical analysis of Open Source Software Defects data through Software Reliability Growth Models [PDF]
, 2013 The purpose of this study is to analyze the reliability growth of Open Source Software (OSS) using Software Reliability Growth Models (SRGM). This study uses defects data of twenty five different releases of five OSS projects.
Najeeb Ullah +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Fourth Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE4)
Journal of Open Research Software, 2018 This article summarizes motivations, organization, and activities of the Fourth Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE4).
Daniel S. Katz +15 more
doaj +1 more source
Geocomputation and open source software: components and software stacks. [PDF]
Geocomputation, with its necessary focus on software development and methods innovation, has enjoyed a close relationship with free and open source software communities. These extend from communities providing the numerical infrastructure for computation,
Bivand, Roger
core
Open Source for Digital Curation [PDF]
, 2005 This Curation Manual instalment discusses at some lengths the relevant strengths of open source software from a digital curation perspective, as well as detailing some of its more general advantages, which must be understood in order to accept the ...
McHugh, Mr Andrew, McHugh, Andrew
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Partnership: The Canadian Journal of Library and Information Practice and Research, 2013 Using open source hardware platforms like the Arduino, libraries have the ability to quickly and inexpensively prototype custom hardware solutions to common library problems.
Jonathan Younker, Tim Ribaric
doaj +1 more source