Results 121 to 130 of about 1,180,256 (306)

Users of Open Source Software - How do they get help?

, 2009
A study was conducted across multiple open source software online technical help communities. This paper presents the types of discussions that occur, the types of questions that are given.
Nichols, David M., David M. Nichols, Twidale, Michael B., Singh, Vandana, Vandana Singh, Michael B. Twidale   +5 more
core   +1 more source

Rezension „Open Source Software“ [PDF]

HMD Praxis der Wirtschaftsinformatik, 2020
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

OpenCSP: Collaborative Code and Data For CSP

SolarPACES Conference Proceedings
We are announcing OpenCSP, an open-source platform including source code, applications, and data to enable collaborative development for the CSP community worldwide, supporting industry, research, and education.
Randy Brost, Benjamin Bean, Felicia Brimigion, Margaret Gordon, Evan Harvey, Madeline Hwang, Tristan Larkin, Miranda Mundt, Nicholas Phelps, Braden Smith, Carly Tanaka-Lubensky   +10 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The Adoption of Open-Source software’s in Libraries in Digital Era

Journal of Information Management and Practices
This study aims to explore the adoption of Open-Source Software’s (OSS) in the academic libraries of Pakistan. It also focuses on the challenges encountered during the application and management of these software’s in both public and private sectors ...
Dr. Shahzad Ahmad, Muhammad Ibrahim, Dr. Sajjad Ahmad, Abid Hussain   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Formal Assessment of Agreement and Similarity between an Open-Source and a Reference Industrial Device with an Application to a Low-Cost pH Logger

Sensors
Open-source devices are nowadays used in a vast number of research fields like medicine, education, agriculture, and sports, among others. In this work, an open-source, portable, low-cost pH logger, appropriate for in situ measurements, was designed and ...
Evmorfia P. Bataka, Persefoni Maletsika, Christos T. Nakas   +2 more
doaj   +1 more source

PAPRECA: a parallel hybrid off-lattice kinetic Monte Carlo/molecular dynamics simulator

Kinetic Monte Carlo (kMC) is an atomistic and stochastic simulation technique that captures the temporal evolution of various systems in materials science, chemistry, physics, biology, and engineering.
Ntioudis, Stavros, Dini, Daniele, Turner, C Heath, Ewen, James P   +3 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source