Results 41 to 50 of about 1,658,706 (311)

Evaluating the Evacuation and Rescue Capabilities of Urban Open Space from a Land Use Perspective: A Case Study in Wuhan, China

open access: yesISPRS International Journal of Geo-Information, 2017
This study proposes an innovative integrated method for evaluating the evacuation and rescue capabilities of open spaces through a case study in Wuhan, China.
Jie Gong   +4 more
doaj   +1 more source

Lessons from the Santa Monica Mountains: Continuing the cycle of conservation

open access: yesFrontiers in Sustainable Cities, 2022
Spanning more than 73 km across two counties at the western border of the Los Angeles metropolitan area, the Santa Monica Mountains represent both a major landform as well as a unique urban-adjacent open space for millions of residents throughout ...
Daniel S. Cooper   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Global Distribution and Seasonality of Martian Atmospheric HCl Explained Through Heterogeneous Chemistry

open access: yesGeophysical Research Letters
Recent observations from the ExoMars Trace Gas Orbiter (TGO) have revealed the presence of hydrogen chloride (HCl) in the martian atmosphere. HCl shows strong seasonality, primarily appearing during Mars' perihelion period before decreasing faster than ...
Paul M. Streeter   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The viscosity and processing of molten lunar regolith

open access: yesScientific Reports
Establishing a permanent, self-sufficient habitat for humans on planetary bodies is critical for successful space exploration. In-situ resource utilisation (ISRU) of locally available resources offers the possibility of an energy-efficient and cost ...
James Bowen   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Open Space – a collaborative process for facilitating Tourism IT partnerships

open access: yes, 2008
The success of IT projects depends on the success of the partnerships on which they are based. However past research by the author has identified a significant rate of failure in these partnerships, predominantly due to an overly technical mindset ...
Philip Alford, Alford, Philip
core   +1 more source

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