Results 141 to 150 of about 1,658,706 (311)

What Affects Older Adults' Viewing Behaviors in Neighborhood Open Space: A Study in Hong Kong. [PDF]

Int J Environ Res Public Health, 2021
He MF, Shi SL, He MY, Leng YP, Wang SY.
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Access to and Quality of Neighbourhood Public Open Space and Children's Mental Health Outcomes: Evidence from Population Linked Data across Eight Australian Capital Cities. [PDF]

Int J Environ Res Public Health, 2022
Alderton A, O'Connor M, Badland H, Gunn L, Boulangé C, Villanueva K.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Willamette River Open Space Vision and Action Plan

, 2013
The Willamette River Open Space Vision is intended to provide an inspirational view of how the diverse open space network that lines the Willamette River and its tributaries in and around the Eugene-Springfield metro area can be enhanced in the years and
Krueger, Jeff
core  

Editorial: Historical Legacies of Land Use in Cities; Parks, Open Spaces and Potential for Green Infrastructure- Ideas of City Nature in an Urbanizing Planet

Frontiers in Ecology and Evolution, 2021
Stephanie Pincetl, Stephanie Pincetl, Jason Antony Byrne   +2 more
doaj   +1 more source

Aesthetic–Restorative Qualities and Social Interaction in Public Open Spaces: Investigating the Pathways to Place Attachment

Architecture
Place attachment, or the emotional bond between people and physical settings, is a central concept in urban design and environmental psychology. Although biophilic and restorative environmental frameworks have stressed the value of natural environments ...
Sana Al-Azzawi, Göksenin İnalhan, Nada Al-Azzawi   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Introducing open montage:Material performativity in urban media configurations in space [PDF]

This article introduces the concept of ‘open montage’, a framework developed to explore the media configurations between art, cinema, and urban space and the entangled relations this interplay presents in terms of publics and publicness.
Jordan, Mel, Mel Jordan, Giorgia Rizzioli, Rizzioli, Giorgia   +3 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source