Results 171 to 180 of about 20,792,994 (299)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Open space race

, 1994
Mary Davey to run in Ward 2 for seat on the Midpeninsula Regional Open Space District ...
Palo Alto Weekly
core  

Does respiratory co-infection facilitate dispersal of SARS-CoV-2? Investigation of a super-spreading event in an open-space office [PDF]

Antimicrob Resist Infect Control, 2020
Weissberg D, Böni J, Rampini S, Kufner V, Zaheri M, Schreiber PW, Abela IA, Huber M, Sax H, Wolfensberger A.   +9 more
europepmc   +2 more sources

What are the topics you care about making trials in lupus more effective? Results of an Open Space meeting of international lupus experts. [PDF]

Lupus Sci Med, 2021
Mucke J, Alarcon-Riquelme M, Andersen J, Aringer M, Bombardieri S, Brinks R, Cervera R, Chehab G, Cornet A, Costedoat-Chalumeau N, Czirják L, Doria A, Fischer-Betz R, Furie RA, Gatto M, Houssiau FA, Ines L, Liang MH, Morand E, Mosca M, Pego-Reigosa JM, Rúa-Figueroa I, Ruiz-Irastorza G, Terrier B, Voss A, Schneider M.   +25 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Examining privilege and power in US urban parks and open space during the double crises of antiblack racism and COVID-19. [PDF]

Socioecol Pract Res, 2021
Hoover FA, Lim TC.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

SOAR-RL: Safe and Open-Space Aware Reinforcement Learning for Mobile Robot Navigation in Narrow Spaces. [PDF]

Sensors (Basel)
Jun M, Park P, Jung H.
europepmc   +1 more source

Inclusive Parks across Ages: Multifunction and Urban Open Space Management for Children, Adolescents, and the Elderly. [PDF]

Int J Environ Res Public Health, 2020
Sundevall EP, Jansson M.
europepmc   +1 more source