Results 101 to 110 of about 1,318,208 (259)

Pixel-based open-space microfluidics for versatile surface processing. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Goyette PA   +3 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Sensory stimulation in campus open spaces for salutogenic effects: a scoping review of literature

open access: yesJournal of Asian Architecture and Building Engineering
Sensory design is increasingly applied in therapeutic and educational environments to promote well-being. Within urban universities, sensory stimulation is posited to significantly enhance the salutogenic effects of campus open spaces, as an appealing ...
Mengjia Fan   +2 more
doaj   +1 more source

What Affects Older Adults' Viewing Behaviors in Neighborhood Open Space: A Study in Hong Kong. [PDF]

open access: yesInt J Environ Res Public Health, 2021
He MF, Shi SL, He MY, Leng YP, Wang SY.
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The Peregrine Ion Trap Mass Spectrometer (PITMS) Investigation Development and Preflight Planning

open access: yesThe Planetary Science Journal
The Peregrine Ion Trap Mass Spectrometer (PITMS) is a mass spectrometer instrument that operated during the Astrobotic Peregrine Mission-1 as part of the NASA Commercial Lunar Payload Services initiative.
Barbara A. Cohen   +36 more
doaj   +1 more source

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