Results 51 to 60 of about 22,332,829 (306)

Tree canopy coverage at urban areas - concept and method

GEOUSP: Espaço e Tempo, 2006
We notice a great confusion in respect to the terms used to identify the green of the nature in the city. Among corporations of research, education and planning, we find different versions of terms for green area, open space, tree canopy coverage, these ...
João Carlos Nucci, Felisberto Cavalheiro   +1 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Open-Fracture Patient Evaluation Nationwide (OPEN) study : epidemiology of open fracture care in the UK. [PDF]

, 2022
AIMS: Understanding of open fracture management is skewed due to reliance on small-number lower limb, specialist unit reports and large, unfocused registry data collections. To address this, we carried out the Open Fracture Patient Evaluation Nationwide (
Trompeter, A, Hadfield, JN, Walker, R, Bretherton, CP, Open Fracture Patient Evaluation Nationwide (OPEN) collaborators, Eardley, WGP, Gray, A, Omogbehin, TS, Brookes, C, Christopher P. Bretherton, Eardley, William G. P., William G. P. Eardley, Reece Walker, Brookes, Charlotte, Omogbehin, Tomisin S., Tomisin S. Omogbehin, Trompeter, Alex, Charlotte Brookes, Alex Trompeter, Andrew Gray, Walker, Reece, Bretherton, Christopher P., Gray, Andrew, James N. Hadfield, Hadfield, James N.   +24 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Predicting space climate change [PDF]

, 2011
The recent decline in the open magnetic flux of the Sun heralds the end of the Grand Solar Maximum (GSM) that has persisted throughout the space age, during which the largest‐fluence Solar Energetic Particle (SEP) events have been rare and Galactic ...
L. Barnard, Owens, Matt J., M. A. Hapgood, Owens, M. J., Lockwood, M., C. J. Davis, M. J. Owens, Barnard, L., M. Lockwood, F. Steinhilber, Steinhilber, F., Davis, Chris J., Hapgood, M. A., Davis, C. J., Davis CJ, Owens MJ, Lockwood M, Hapgood MA, Steinhilber F, Barnard L, Hapgood, M.A. (author), Davis, C.J. (author), Barnard, L. (author), Steinhilber, F. (author), Owens, M.J. (author), Lockwood, M. (author)   +25 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Grottoes, VA: Conceptual Open Space Master Plan and Entrance Design

, 2022
The Community Design Assistance Center (CDAC) worked with the town of Grottoes to create entryway designs for the primary entries to town as well as Sixth Street, which serves as the town’s “Main Street.” CDAC also prepared an open space master plan ...
Gilboy, Elizabeth, Watson, Kim, Jessup, Jennifer, Brown, Julia   +3 more
core  

Global Distribution and Seasonality of Martian Atmospheric HCl Explained Through Heterogeneous Chemistry

Geophysical Research Letters
Recent observations from the ExoMars Trace Gas Orbiter (TGO) have revealed the presence of hydrogen chloride (HCl) in the martian atmosphere. HCl shows strong seasonality, primarily appearing during Mars' perihelion period before decreasing faster than ...
Paul M. Streeter, Kylash Rajendran, Stephen R. Lewis, Kevin S. Olsen, Alexander Trokhimovskiy, Oleg Korablev, Manish R. Patel   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The viscosity and processing of molten lunar regolith

Scientific Reports
Establishing a permanent, self-sufficient habitat for humans on planetary bodies is critical for successful space exploration. In-situ resource utilisation (ISRU) of locally available resources offers the possibility of an energy-efficient and cost ...
James Bowen, Vibha Levin Prabhu, Sungwoo Lim, Mahesh Anand   +3 more
doaj   +1 more source