Results 111 to 120 of about 20,097,814 (257)

Introducing open montage:Material performativity in urban media configurations in space [PDF]

open access: yes
This article introduces the concept of ‘open montage’, a framework developed to explore the media configurations between art, cinema, and urban space and the entangled relations this interplay presents in terms of publics and publicness.
Jordan, Mel   +3 more
core   +1 more source

Iris: Deep Space Small Satellite Radio [PDF]

open access: yes, 2017
With nanosatellites being used for deep space missions, the need for a unique communications architecture to relay valuable mission data back to NASA’s Deep Space Network (DSN) is ...
Space Dynamics Laboratory
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Digital systems and tools to support urban open space governance and management

open access: yes, 2020
This chapter outlines how digital systems and tools can support urban open space (UOS) governance and management and discusses important factors to consider when building a strategy in relation to future trends and routes to progress. A key conclusion is
Deak Sjöman, Johanna,   +5 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

History of Open Space and Physical Activities of China’s Danwei Neighborhood: The Case Study of Community Hua

open access: yesBuildings
The danwei community emerged as a basic socio-spatial unit in China’s urban landscape, primarily constructed in the mid-20th century. Today, amid population aging and the deterioration of service facilities supporting health environment, the mental and ...
Hanxiao Heng, Xuan He, Nina Mo
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Sunlight as a common good. A comparative study of the overshadowing of public spaces adjacent to contemporary multifamily housing developments based on the Wrocław example

open access: yesTechnical Transactions
Sunlight plays a crucial role in everyday life. Contemporary regulations and research emphasize solar access to buildings, with more limited consideration to open spaces (OSs).
Kazanecka-Olejnik Lea
doaj   +1 more source

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