Results 91 to 100 of about 20,809,034 (299)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Trade-off between Private Lots and Public Open Space in Subdivisions at the Urban-Rural Fringe [PDF]

open access: yes
In many communities on the urban–rural fringe, subdivisions are subject to “clustering” rules, in which houses must be located on a portion of the total land area and the remainder of the land is left as open space.
McConnell, Virginia D.   +2 more
core  

Evaluating the Evacuation and Rescue Capabilities of Urban Open Space from a Land Use Perspective: A Case Study in Wuhan, China

open access: yesISPRS International Journal of Geo-Information, 2017
This study proposes an innovative integrated method for evaluating the evacuation and rescue capabilities of open spaces through a case study in Wuhan, China.
Jie Gong   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Open Space and Urban Sprawl: The Effects of Zoning and Forest Conservation Regulations in Maryland [PDF]

open access: yes
Rapid urbanization enhances the desirability of policies for preserving open space but policies intended to preserve open space may extend the urban boundary and create leapfrog development.
Lichtenberg, Erik
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

A Taste for Trips out of Town: Urban Sprawl and Access to Open Space [PDF]

open access: yes
Residential development at the urban fringe raises the cost of trips to open space. We derive a simple expression for the tax that internalizes this effect of sprawl in a monocentric city andapply it using survey data on recreational activity.
Wouter Vermeulen, Jan Rouwendal
core  

Reducing the prosthesis modulus by inclusion of an open space lattice improves osteogenic response in a sheep model of extraarticular defect. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Sanaei R   +12 more
europepmc   +1 more source

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