Results 51 to 60 of about 20,792,994 (299)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microclimate governs the morphology of sediment flows on Mars

Communications Earth & Environment
Landforms created by flowing water with sediment have left deposits on the surface of Mars, allowing study of the ancient environment. These features could provide constraints on surface water activity and past habitability.
Jacob B. Adler, Frances Rivera-Hernández, Sharissa Thompson, Petr Brož, Matthew E. Sylvest, Zoe S. Emerland, Manish Patel, Mark Fox-Powell   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tree canopy coverage at urban areas - concept and method

GEOUSP: Espaço e Tempo, 2006
We notice a great confusion in respect to the terms used to identify the green of the nature in the city. Among corporations of research, education and planning, we find different versions of terms for green area, open space, tree canopy coverage, these ...
João Carlos Nucci, Felisberto Cavalheiro   +1 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Global Distribution and Seasonality of Martian Atmospheric HCl Explained Through Heterogeneous Chemistry

Geophysical Research Letters
Recent observations from the ExoMars Trace Gas Orbiter (TGO) have revealed the presence of hydrogen chloride (HCl) in the martian atmosphere. HCl shows strong seasonality, primarily appearing during Mars' perihelion period before decreasing faster than ...
Paul M. Streeter, Kylash Rajendran, Stephen R. Lewis, Kevin S. Olsen, Alexander Trokhimovskiy, Oleg Korablev, Manish R. Patel   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The viscosity and processing of molten lunar regolith

Scientific Reports
Establishing a permanent, self-sufficient habitat for humans on planetary bodies is critical for successful space exploration. In-situ resource utilisation (ISRU) of locally available resources offers the possibility of an energy-efficient and cost ...
James Bowen, Vibha Levin Prabhu, Sungwoo Lim, Mahesh Anand   +3 more
doaj   +1 more source