Results 31 to 40 of about 20,097,814 (257)
Evaluating Lethal and Nonlethal Management Options for Urban Coyotes
Human-coyote conflict in urban environments is a growing issue in cities throughout the United States with the primary problem being the development of problem individuals that are overly bold and aggressive with people and pets.
Stewart W. Breck +2 more
doaj +1 more source
A framework for designing the open spaces in the children’s educational centers based on the (Seven Cs) with emphasis on pProve the learning [PDF]
The main purpose of this study was to identify the effectiveness factors in the design of open space in educational centers for children and its relationship to learning. Because learning and convey the meaning is an inseparable part in every educational
M. Khakzand, S. Babaei
doaj +1 more source
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
The relevance of the article is due to the lack of attention to the issues of studying literary works through the prism of the concepts of artistic time and space in Literature lessons at school.
Gulnaz Nurfatovna Mukharlyamova +1 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protected area management bodies are increasingly required to address economic development alongside the original goal of conservation. This is especially true for United Nations Educational, Scientific and Cultural Organization (UNESCO) biosphere ...
Florian Knaus +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

