Results 71 to 80 of about 20,097,814 (257)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Advancing Heliophysics and Space Weather Modeling through Open Science [PDF]

We present a community-wide effort to develop a strategy and action plan to advance heliophysics and space weather modeling through open science.
Kondrashov, D., Ganushkina, N., Omelchenko, Y. A., Themens, D. R.; id_orcid, Weigel, R. S., Merkin, V., Chartier, A., Wilhelm, R.‐P., Wang, J., Georgoulis, M. K., Elvidge, S.; id_orcid, Delzanno, G. L., Pandey, C., Caplan, R. M., Tsui, T., Yue, J., Mayank, P., Landwer, L. J., Verbeke, C., Kodikara, T., Jordanova, V., Taktakishvili, A., Karpen, J., Zakharenkova, I., Tenishev, V., Petrenko, M., Odstrcil, D., Faturahman, A., Reiss, M. A., De Zeeuw, D., Didigu, C., Liu, W., Sur, D., Shi, C., Luhmann, J. G., Bruinsma, S., Cecconi, B., Garcia‐Sage, K., Mehta, P. M., Zhang, K., Rastätter, L., Linker, J. A., Wiltberger, M., Rusaitis, L., Bisi, M. M., DeVore, C. R., Mays, M. L., Arge, C. N., Pulkkinen, T., Huang, Z., Masson, A., Deka, P. J., Sachdeva, N., Moens, N., Fung, S., Topper, J., Liu, H., Daldorff, L. K. S., Ridley, A. J., Chou, M.‐Y., Bacchini, F., Ledvina, V. E., Young, M. A., Jian, L. K., Jackson, B. V., Samara, E., Provornikova, E., Markidis, S., Palmerio, E., Green, J., Zheng, Y., Poedts, S., Whitman, K., Resnick, E., da Silva, D., Kuznetsova, M. M., Bard, C., MacNeice, P., Miesch, M. S., Wang, W., Corti, C., Huba, J. D., Wiegand, C., Shou, Y., Toth, G., El Alaoui, M., Bacchini F, Zhang, K.,, Elvidge S, Caplan, R.M., Markidis, Stefano,, Ridley AJ, Pulkkinen T, Elvidge, S., Omelchenko, Y.A., Garcia-Sage, K., Reiss MA, palmroth, M., Rusaitis L, Weigel RS, Young, M.A., Kuznetsova, M.M., Huba JD, Georgoulis, M.K., Rastätter L, Mehta, P.M., Jackson BV, El Alaoui M, Delzanno, G.L., Omelchenko YA, Green J, Miesch, M.S., Palmroth, Minna Maria Emilia, Moens N, Deka PJ, Mays ML, Taktakishvili A, Bard C, Garcia‐Sage K, Sur D, Caplan RM, Themens DR, Didigu C, Linker, J.A., Bisi MM, Themens, D. R., Miesch MS, Poedts S, Lesko M, Deka, P.J., Jackson, B.V., Mays, M.L., Daldorff LKS, et al., Liu H, Markidis S, Odstrcil D, Landwer LJ, Arge, C.N., Liu W, Wilhelm R, Petrenko M, Ridley, A.J., Chou M, Samara E, Topper J, Pandey C, Cecconi B, Themens, D.R., Sachdeva N, Kodikara T, Corti, C.,, De Zeeuw D, MacNeice P, Georgoulis MK, Zhang K, Tsui T, Luhmann, J.G., Chou, M-Y., Fung S, Jian LK, lesko, M., Shou Y, Wilhelm, R-P., Toth G, Zheng Y, Linker JA, Verbeke C, Ganushkina N, Ledvina VE, Landwer, L.J., Kondrashov D, Wiegand C, Jordanova V, DeVOre, C.R., Palmerio E, Poedts, Stefaan, Huang Z, Shi C, Huba, J.D., Mehta PM, Weigel, R.S., Wang J, Yue J, Mayank P, Resnick E, Corti C, Luhmann JG, Provornikova E, Wang W, da Silva D, Merkin V, Daldorff, L.KS., Zakharenkova I, DeVore CR, Young MA, Chartier A, Karpen J, Delzanno GL, Wiltberger M, Ledvina, V.E., Samara, Evangelia, Bisi, M.M., Jian, L.K., Whitman K, Kuznetsova MM, Tenishev V, Masson A, Arge CN, Bruinsma S, Faturahman A, Palmroth M, Reis, M.A.   +212 more
core   +1 more source

Open science in space [PDF]

Nature Medicine, 2021
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

[Save Open Space, March 02, 1973, Press Conference Announcement]

, 1973
A press release issued by the environmental group, Save Open Space, announcing a press conference at the Press Club of Dallas on March 7, 1973. The subject is the Trinity River canal project which was on the ballot of the bond election of March 13, 1973.
Save Open Space
core  

Willamette River Open Space Vision and Action Plan [PDF]

, 2013
The Willamette River Open Space Vision is intended to provide an inspirational view of how the diverse open space network that lines the Willamette River and its tributaries in and around the Eugene-Springfield metro area can be enhanced in the years and
Krueger, Jeff
core  

Planifier avec le territoire : la dynamique des lieux de projets à l’épreuve des approches participatives et paysagères

VertigO, 2019
Since the late 1990s, the soaring issues related to sustainability coupled with the ongoing process of metropolization have generated a progressive renewal of territorial planning methods.
Benoît Dugua, Leila Chakroun
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Open Space Purchases, House Prices, and the Tax Base [PDF]

This paper examines the effect of public acquisitions of open space on house prices and the municipal tax base. While a series of studies show that open space acquisitions raise values of nearby properties, no research to date appears to focus upon the ...
Michael, Lahr, Donald, Vandegrift
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source