Results 91 to 100 of about 1,541,414 (259)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Sunlight as a common good. A comparative study of the overshadowing of public spaces adjacent to contemporary multifamily housing developments based on the Wrocław example

open access: yesTechnical Transactions
Sunlight plays a crucial role in everyday life. Contemporary regulations and research emphasize solar access to buildings, with more limited consideration to open spaces (OSs).
Kazanecka-Olejnik Lea
doaj   +1 more source

Perception of open urban space – Bevk square in Nova Gorica [PDF]

open access: yesUrbani Izziv, 1997
In research on perception of open urban space, psychological and structural aspects are important, as well as social use. Social use however is most important, because open urban space and its green surfaces satisfies needs of an urban population.
Nataša Bratina
doaj  

Hydrogen cyanide and carboxyhemoglobin assessment in an open space fire-related fatality. [PDF]

open access: yesJ Forensic Sci, 2021
Tabian D   +5 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Exploring open and green space characteristics for climate change adaptation: a focus on flooding phoenomenon

open access: yesTeMA: Journal of Land Use, Mobility and Environment
Starting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always remaining in the groove of rigorous scientific in-depth analysis. This section of the Journal, Review Notes,
Tonia Stiuso
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Sensory stimulation in campus open spaces for salutogenic effects: a scoping review of literature

open access: yesJournal of Asian Architecture and Building Engineering
Sensory design is increasingly applied in therapeutic and educational environments to promote well-being. Within urban universities, sensory stimulation is posited to significantly enhance the salutogenic effects of campus open spaces, as an appealing ...
Mengjia Fan   +2 more
doaj   +1 more source

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