Results 151 to 160 of about 137,348 (307)

Using Detailed Single-star and Binary-evolution Models to Probe the Large Observed Luminosity Spread of Red Supergiants in Young Open Star Clusters

The Astrophysical Journal Letters
Red supergiants (RSGs) represent a late evolutionary stage of massive stars. Recent observations reveal that the observed luminosity range of RSGs in young open clusters is wider than expected from single-star evolution models.
Chen Wang, Lee Patrick, Abel Schootemeijer, Selma E. de Mink, Norbert Langer, Nikolay Britavskiy, Xiao-Tian Xu, Julia Bodensteiner, Eva Laplace, Ruggero Valli, Alejandro Vigna-Gómez, Jakub Klencki, Stephen Justham, Cole Johnston, Jing-ze Ma   +14 more
doaj   +1 more source

Observations of 14 young open star clusters with the HEGRA system of Cherenkov telescopes [PDF]

, 2006
F. Aharonian, A. G. Akhperjanian, M. Beilicke, K. Bernlöhr, H. Börst, H. Bojahr, O. Bolz, T. Coarasa, J. L. Contreras, J. Cortina, S. Denninghoff, M. V. Fonseca, M. Girma, N. Götting, G. Heinzelmann, G. Hermann, Andréas Heusler, W. Hofmann, D. Horns, I. Jung, R. Kankanyan, M. Kestel, A. Konopelko, H. Kornmeyer, D. Kranich, H. Lampeitl, Marcos López, E. Lorenz, F. Lucarelli, O. Mang, H. Meyer, R. Mirzoyan, A. Moralejo, E. de Oña Wilhelmi, M. Panter, A. Plyasheshnikov, G. Pühlhofer, R. de los Reyes, W. Rhode, J. Ripken, Gavin Rowell, V. Sahakian, M. Samorski, M. Schilling, M. Siems, D. Sobzynska, W. Stamm, M. Tluczykont, V. Vitale, H. J. Völk, C. A. Wiedner, W. Wittek   +51 more
openalex   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Single star scattering on an open cluster [PDF]

, 2007
Alexey Mints, Patrick Glaschke, Rainer Spurzem   +2 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

The Present-day Mass Function of Star Clusters in the Solar Neighborhood

The Astrophysical Journal
This work analyzes the present-day mass function (PDMF) of 93 star clusters utilizing Gaia Data Release 3 data, with membership determined by the StarGo machine-learning algorithm.
Xiaoying Pang, Siqi Liao, Jiadong Li, Zhiqiang Yan, Mingjie Jian, M. B. N. Kouwenhoven, Shih-Yun Tang, Yifan Wang   +7 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

From Star Complexes to the Field: Open Cluster Families [PDF]

, 2008
R. de la Fuente Marcos, C. de la Fuente Marcos   +1 more
openalex   +1 more source