Results 161 to 170 of about 239,741 (340)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Bayesian and Statistical Analysis of the Open Star Cluster NGC 6416 [PDF]

Simanta Deka
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Census of Pulsars in Possible Association with Galactic Open Clusters

The Astrophysical Journal Letters
Among the ∼4000 known pulsars in our Galaxy, ≲10% are found in globular clusters, but none has been confirmed in any open clusters yet, although they outnumber globular clusters by about 20 times.
Lu Zhou, Zhi-Qiang You, Lu Li, Xiao-Jin Liu, Xing-Jiang Zhu, Zong-Hong Zhu   +5 more
doaj   +1 more source

Variable stars in young open star cluster NGC 7380 [PDF]

, 2015
Sneh Lata, A. K. Pandey, Neelam Panwar, Wen-Ping Chen, M. R. Samal, J. C. Pandey   +5 more
openalex   +1 more source

Tidal tails of open star clusters as probes to early gas expulsion [PDF]

, 2020
František Dinnbier, Pavel Kroupa
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Census of Blue Straggler Stars in Distant Open Clusters and Maximum Fractional Mass Excess of Open Cluster Blue Straggler Stars

The Astronomical Journal
We identified blue straggler stars (BSSs) in 53 open clusters utilizing data from Gaia DR3. Most of these clusters are situated in the outer regions of the Galactic disk, encompassing structures such as the warp and the Outer arm.
Qian Cui, Zhihong He, Shunhong Deng, Liming Peng, Chunyan Li, Yangping Luo, Kun Wang   +6 more
doaj   +1 more source

A Hot DQ White Dwarf in the Open Star Cluster M35 [PDF]

, 2006
Kurtis A. Williams, James Liebert, Michael Bolte, Robert B. Hanson   +3 more
openalex   +1 more source