Protocol to analyze changes in hippocampal neural stem cell quiescence from single-cell RNA sequencing data. [PDF]
Hart J, Harris L.
europepmc +1 more source
Young open clusters in the Galactic star forming region NGC 6357 [PDF]
F. Massi +5 more
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Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
A cosmic-ray loaded nascent outflow driven by a massive star cluster. [PDF]
Lemoine-Goumard M +8 more
europepmc +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Astrocytes: The Unsung Architects of Synaptic Integration and Their Role in Brain Health and Disease. [PDF]
Elvira R, Tan EK, Zhou ZD.
europepmc +1 more source
A search for rapidly oscillating AP stars. I - The Ap-rich open cluster NGC 2516. II - Evidence for oscillations in the field star HD 116763 [PDF]
J. M. Matthews +2 more
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Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
<i>Neisseria gonorrhoeae</i> LIN codes provide a robust, multi-resolution lineage nomenclature. [PDF]
Unitt A +5 more
europepmc +1 more source
The very rich massive post-main-sequence star population of the open cluster Westerlund 1 [PDF]
I. Negueruela, J. S. Clark
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