Results 241 to 250 of about 134,869 (325)

Spatial Heterogeneity, Stromal Phenotypes, and Therapeutic Vulnerabilities in Colorectal Cancer Peritoneal Metastasis. [PDF]

Clin Cancer Res
Ong CJ, Zhao JJ, Liu Y, Srivastava S, Chia DKA, Quek YE, Fan X, Ma H, Huang KK, Sheng T, Tan QX, Ng G, Tan JWS, Lee JJ, Loo LH, Chong LY, Ong XW, Tay ST, Hagihara T, Tan A, Joseph CRC, Teo MCC, Hendrikson J, Chong CYL, Guo W, Chia CS, Wong JSM, Seo CJ, Cai M, Tay Y, Sim KMS, Tay RYK, Walsh R, Guaglio M, Morano F, Teh M, Lum HYJ, Lim TKH, Vermeulen L, Bijlsma MF, Lenos K, Klempner SJ, Yeong JPS, Yong WP, Pietrantonio F, Tan P, Sundar R.   +46 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Protocol for achieving enhanced snRNA-seq data quality using Quality Clustering. [PDF]

STAR Protoc
Tavi PJ, Ojanen J, Laitinen P, Linna-Kuosmanen S.   +3 more
europepmc   +1 more source

Fundamental Parameters of Some New Discovered Open star Clusters

, 2010
R. El-Bendary, A. L. Tadross
openalex   +2 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Competing dynamic gene regulatory networks involved in fibroblast reprogramming to hematopoietic progenitor cells. [PDF]

Stem Cell Reports
Shafiq S, Hamashima K, Guest LA, Al-Anbaki AH, Amaral FMR, Wiseman DH, Kouskoff V, Lacaud G, Loh YH, Batta K.   +9 more
europepmc   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

AI-based body composition analysis of CT data has the potential to predict disease course in patients with multiple myeloma. [PDF]

Sci Rep
Wegner F, Sieren MM, Grasshoff H, Berkel L, Rowold C, Röttgerding MP, Khalil S, Mogadas S, Nensa F, Hosch R, Riemekasten G, Hamm AF, von Bubnoff N, Barkhausen J, Kloeckner R, Khandanpour C, Leitner T.   +16 more
europepmc   +1 more source

Brightest Stars in Open Clusters.

The Astronomical Journal, 1963
openaire   +3 more sources

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source