Results 271 to 280 of about 239,741 (340)

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey, Jennifer M. Farmer, David R. Lynch   +2 more
wiley   +1 more source

Earth-mass planets with He atmospheres in the habitable zone of Sun-like stars. [PDF]

Nat Astron
Lammer H, Scherf M, Erkaev NV, Kubyshkina D, Gorbunova KD, Fossati L, Woitke P.   +6 more
europepmc   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

A Biocompatible and Self-Healable 3D-Printed Bidirectional Hydrogel Actuator with Needle Injectability. [PDF]

ACS Appl Mater Interfaces
Yang KR, Cheng QP, Hsu SH.
europepmc   +1 more source

Characterization of the Blue Straggler Star Populations, through Statistical, Photometric, and Spectral Energy Distribution Analysis, in the Old Open Cluster: NGC 2243

A H Sheikh, Biman J. Medhi
openalex   +1 more source

Asymmetry of the tidal tails of open star clusters in direct N-body integrations in Milgrom-law dynamics [PDF]

J. Pflamm-Altenburg
openalex   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan. [PDF]

Cell Rep Methods
Eling N, Dorier J, Rusakiewicz S, Liechti R, Devanand P, Daniel M, Windhager J, Fernandez BP, Déglise S, Despland L, Benyagoub A, Możejko M, Uchal D, Szczurek E, Loboda A, Sandkuijl D, Parsotam N, Hong HS, Morfouace M, Guex N, Coukos G, Bodenmiller B, Tissot S, Schulz D.   +23 more
europepmc   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Protocol for the quantitative characterization of cell aggregates using an MRI setup maintaining optimal cultivation conditions. [PDF]

STAR Protoc
Wißmann R, Martirosian P, Danalache M, Elser S, Schick F.   +4 more
europepmc   +1 more source