Results 101 to 110 of about 1,821,718 (352)

Laparoendoscopic single-site retroperitoneoscopic adrenalectomy compared with conventional laparoscopy and open surgery

open access: yesUrological Science, 2017
Objective: Laparoendoscopic single-site surgery (LESS) is a new laparoscopy development that avoids the use of multiple ports and minimizes morbidity. Combined with retroperitoneoscopy, LESS is suitable for adrenalectomy.
Szu-Han Chen   +6 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Open Versus Laparoscopic Appendectomy for Perforated Appendicitis: A Randomized Prospective Study

open access: yesPakistan Journal of Medical Research, 2020
Objective: To compare the mean hospital stay, mean operative time and frequency of port site infections in patients with early-perforated appendix managed laparoscopically versus open approach.
Aamna Nazir   +3 more
doaj  

Open Surgery for Spiegel's Hernia

open access: yesInternational Journal Of Medical Science And Clinical Research Studies, 2023
Spiegel's hernias are uncommon anomalies in the Spiegel's aponeurosis, which runs between the rectus muscle and the semilunar line. They are most commonly found in the "Spigel's hernia belt" between the navel and the interspinal line (a horizontal line connecting the anterosuperior iliac spines). We recommend open repair for individuals who arrive with
openaire   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

ANESTHETIC PROBLEMS IN CARDIOPULMONARY BYPASS FOR OPEN HEART SURGERY [PDF]

open access: bronze, 1958
Arthur S. Keats   +3 more
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Surgical and Early Oncological Outcomes of Laparoscopic Versus Open Rectal Surgery: A Comparative Study

open access: yesTurkish Journal of Colorectal Disease, 2019
Aim:In this study, we aimed to evaluate the short-term clinicopathological outcomes of laparoscopic versus open surgery in patients undergoing rectal cancer surgery.Method:Between May 2015 and July 2017, 46 patients who underwent curative surgery for ...
Nidal İflazoğlu   +3 more
doaj   +1 more source

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