Are “European” Scrotal Hernias Repairable With the Minimal Open Pre-Peritoneal Technique?
Journal of Abdominal Wall SurgeryBackgroundMinimally invasive open preperitoneal techniques are an alternative in groin hernia repair. Scrotal hernias (SH) are frequently difficult to repair laparoscopically, resulting in a significant conversion rate.MethodsThe aim of this exploratory ...
Marc Soler, Jean Francois Gillion
doaj +1 more source
Naturality of Heegaard Floer invariants under positive rational contact surgery
, 2018 For a nullhomologous Legendrian knot in a closed contact 3-manifold Y we consider a contact structure obtained by positive rational contact surgery.
Mark, Thomas E., Tosun, Bülent
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Successful management of an aorto-gastric fistula occurring 15 years after oesophagectomy with covered aortic stent graft placement followed by open surgery [PDF]
, 2018 Heena S Chotai +3 more
openalex +1 more source
Comparative evaluation of instrument segmentation and tracking methods in minimally invasive surgery [PDF]
, 2018 Intraoperative segmentation and tracking of minimally invasive instruments is a prerequisite for computer- and robotic-assisted surgery. Since additional hardware like tracking systems or the robot encoders are cumbersome and lack accuracy, surgical ...
Agustinos, Anthony +19 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Open Versus Laparoscopic Appendectomy for Perforated Appendicitis: A Randomized Prospective Study
Pakistan Journal of Medical Research, 2020 Objective: To compare the mean hospital stay, mean operative time and frequency of port site infections in patients with early-perforated appendix managed laparoscopically versus open approach.
Aamna Nazir +3 more
doaj
Outcomes of ab interno trabeculectomy with the trabectome by degree of angle opening. [PDF]
, 2015 AimTo analyse ab interno trabeculectomy (AIT) with the trabectome and combined phacoemulsification with AIT (phaco-AIT) by Shaffer angle grade (SG).MethodsProspective study of AIT and phaco-AIT with narrow angles of SG≤2 versus open angles ≥3.
Bussel, II +4 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source