Results 141 to 150 of about 7,883,414 (352)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Open Versus Laparoscopic Appendectomy for Perforated Appendicitis: A Randomized Prospective Study

Pakistan Journal of Medical Research, 2020
Objective: To compare the mean hospital stay, mean operative time and frequency of port site infections in patients with early-perforated appendix managed laparoscopically versus open approach.
Aamna Nazir, Muhammad Idrees Anwar, Maryam Barkat, Muhammad Atif   +3 more
doaj  

Complex minimal invasive surgery: 3D laparoscopic ureterolysis and ureteral reimplantation in obese patient with retroperitoneal fibrosis after radiotherapy and previous open surgery

, 2022
V.H. Schitcu, M.B. Borz, P.C. Borz, I. Cojocaru, M.A. Nucu, M.I. Pop, V.C. Munteanu   +6 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Braids and symplectic four-manifolds with abelian fundamental group

, 2002
We explain how a version of Floer homology can be used as an invariant of symplectic manifolds with $b_1>0$. As a concrete example, we look at four-manifolds produced from braids by a surgery construction.
Seidel, Paul
core   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Prolonged postoperative ileus in gastric surgery: Is there any difference between laparoscopic and open surgery?

Cancer Medicine, 2019
Background Prolonged postoperative ileus (PPOI) is a common complication after abdominal surgery, but data about risk factors of PPOI for patients with gastric cancer are rare.
Wenquan Liang, Jiyang Li, Wang Zhang, Jie Liu, Mingsen Li, Yunhe Gao, Ning Wang, Jianxin Cui, Kecheng Zhang, Hongqing Xi, Bo Wei, Lin Chen   +11 more
doaj   +1 more source

Journal of Craniofacial Surgery Open: Welcome to the New Era of Education and Research in the Field of Maxillofacial Surgery

, 2023
Marco Cicciù
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Therapeutic Options in Hydatid Hepatic Cyst Surgery: A Retrospective Analysis of Three Surgical Approaches

Diagnostics
Hydatid disease is endemic in certain geographical areas where animal breeding is common, frequently challenging the medical services in these regions. Hydatid cysts most often affect the liver, with damage to other organs accounting for around one-third
Alin Mihetiu, Dan Bratu, Bogdan Neamtu, Dan Sabau, Alexandra Sandu   +4 more
doaj   +1 more source