Results 121 to 130 of about 4,056,472 (267)
Fluoridation of a lizard bone embedded in Dominican amber suggests open-system behavior. [PDF]
PLoS One, 2020 Barthel HJ +3 more
europepmc +1 more source
Decoherence in open Majorana systems
, 2015 Coupling to a thermal bath leads to decoherence of stored quantum information. For a system of Gaussian fermions, the fermionic analog of linear or Gaussian optics, these dynamics can be elegantly and efficiently described by evolution of the system's covariance matrix.
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Journal of Advanced TransportationUnderstanding the conditions that affect takeover time (TOT) in conditional autonomous driving systems remains a challenging issue. The takeover process requires a seamless transition of control from the autonomous system to the driver when the system ...
Kyeongjin Lee +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Gestión y Ambiente, 2012 Los residuos sólidos pueden generar impactos negativos al ambiente y al ser humano por causa de un manejo inadecuado. Las universidades deben contemplar su manejo en las etapas de generación, recolección y disposición final, e incluir su valoración.
KARINA ANDREA RÍOS MONTES +1 more
doaj
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source