Results 91 to 100 of about 3,275,591 (372)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

The EPICS Software Framework Moves from Controls to Physics

, 2019
The Experimental Physics and Industrial Control System (EPICS), is an open-source software framework for high-performance distributed control, and is at the heart of many of the world’s large accelerators and telescopes.
Cobb, T., Dalesio, L., Davidsaver, M., Hartman, S., Hickin, D., Johnson, A., Junkes, H., Kasemir, K., Konrad, M., Korhonen, T., Kraimer, M., Lange, R., Pearson, M., Rivers, M., Sekoranja, M., Shankar, M., Shen, G., Shroff, K., Veseli, S., Vodopivec, K., White, G., Zimoch, D.   +21 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

CU2CL: A CUDA-to-OpenCL Translator for Multi- and Many-core Architectures [PDF]

, 2011
The use of graphics processing units (GPUs) in high-performance parallel computing continues to become more prevalent, often as part of a heterogeneous system.
Feng, Wu-chun, Gardner, Mark, Martinez, Gabriel   +2 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Robust control of decoherence in realistic one-qubit quantum gates

, 2003
We present an open loop (bang-bang) scheme to control decoherence in a generic one-qubit quantum gate and implement it in a realistic simulation. The system is consistently described within the spin-boson model, with interactions accounting for both ...
Bouwmeester D, C D Helon, Gardiner C W, Gardiner C W, Giulini D, J Schmulen, Mancini S, Mozyrsky D, Nielsen M A, Palma G M, Pittenger A O, R Perez, Scully M S, Tombesi P, V Protopopescu, van Kampen N G, Weiss U, Wu L A   +17 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Pengembangan Model Aplikasi Administrasi Pelayanan Kesehatan di Puskemas dengan Cloud Computing Berbasiskan Open Source

ComTech, 2013
Puskemas as community health centers becomes one of the main focuses of development on the agenda of the Government of Indonesia beside education. Therefore, we purpose to develop an affordable online system of health care administration based on open ...
Honni Honni
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source