Results 101 to 110 of about 1,717,601 (330)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Informatics of the Equity Markets - A Collaborative Approach [PDF]
This paper aims to provide a high-level overview upon the information technology that supports the electronic transactions performed on the equity markets.
Claudiu VINTE
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
A FUNCTIONAL SKETCH FOR RESOURCES MANAGEMENT IN COLLABORATIVE SYSTEMS FOR BUSINESS [PDF]
This paper presents a functional design sketch for the resource management module of a highly scalable collaborative system. Small and medium enterprises require such tools in order to benefit from and develop innovative business ideas and technologies ...
Moca Mircea, Silaghi Gheorghe Cosmin
core
bSTAB: an open-source software for computing the basin stability of multi-stable dynamical systems [PDF]
, 2021 M. Stender, Norbert Hoffmann
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Open Educational Resources (OER) for Sustainable Development using Autonomic Cloud Computing System [PDF]
, 2016 Nureni Asafe Yekini +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
BinPo: An open-source code to compute the band structure of two-dimensional electron systems [PDF]
, 2022 Emanuel A. Martínez +2 more
openalex +2 more sources
Fault tolerance systems in open source cloud computing environments–A systematic review
, 2023 K. Vani, S. Sujatha
openalex +2 more sources