Results 111 to 120 of about 1,717,601 (330)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Open Data and Government Governance Innovation

大数据, 2015
Cloud computing makes data sharing,data flow,open data become possible,data becomes the key engine for stimulating productivity.Data is changing from the output of IT system or auxiliary role to assets and production factors.Data is driving big data ...
Yonghua Pan
doaj  

Visualizing Open Computational Systems

, 2006
There is an emerging field in the design and development of complex systems, where systems are built upon components which in themselves are large scale systems – system of systems. Among other things, the system of systems viewpoint emphasises on open complex systems.
openaire   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Performance Characterization of Hardware/Software Communication Interfaces in End-to-End Power Management Solutions of High-Performance Computing Processors

Energies
Power management (PM) is cumbersome for today’s computing systems. Attainable performance is bounded by the architecture’s computing efficiency and capped in temperature, current, and power. PM is composed of multiple interacting layers.
Antonio del Vecchio, Alessandro Ottaviano, Giovanni Bambini, Andrea Acquaviva, Andrea Bartolini   +4 more
doaj   +1 more source

Adequacy Evaluation of Composite Generation and Transmission Systems Using an Open-Source Parallel Computing Toolbox

, 2023
Josif Elias Figueroa, Kush Bubbar, Greg Young-Morris   +2 more
openalex   +1 more source

AutoTriage - An Open Source Edge Computing Raspberry Pi-based Clinical Screening System [PDF]

, 2020
Chaitra Hegde, Zifan Jiang, Pradyumna Byappanahalli Suresha, Jacob S. Zelko, Salman Seyedi, Monique A. Smith, David W. Wright, Rishikesan Kamaleswaran, Matt A. Reyna, Gari D. Clifford   +9 more
openalex   +1 more source