Results 121 to 130 of about 1,717,601 (330)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Code and Data for "Nonlinearity of the Fidelity in Open Qudit Systems: Gate and Noise Dependence in High-dimensional Quantum Computing" [PDF]

Jean-Gabriel Hartmann, Denis Janković, R. Pasquier, Mario Ruben, Paul-Antoine Hervieux   +4 more
openalex   +1 more source

Towards Services-Based Enterprise Architecture for Cloud Computing-Opened Information Systems [PDF]

, 2015
M’barek El Haloui, Houda Kriouile, Abdelaziz Kriouile   +2 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Construction of a SDN Driven Novel Service System for Operatiors

Dianxin kexue, 2014
In the mobile internet environment, the major service abilities of operators are gradually losing their advantages. The internet service environment requires an open, flexible, operational architecture.
Jie Liu, Zhe Wang
doaj   +2 more sources

Information Dimension Matching in Memristive Computing System for Analog Deployment of Deep Neural Networks

Advanced Electronic Materials
Memristor, with the ability of analog computing, is widely investigated for improving the computing efficiency of deep neural networks (DNNs) deployment. However, how to fully take advantage of the analog computing ability of memristive computing system (
Zhe Feng, Zuheng Wu, Xu Wang, Xiuquan Fang, Xumeng Zhang, Jianxun Zou, Jian Lu, Wenbin Guo, Xing Li, Tuo Shi, Zuyu Xu, Yunlai Zhu, Fei Yang, Yuehua Dai, Qi Liu   +14 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Architecting Resilient Computing Systems: Overall Approach and Open Issues

, 2011
Miruna Stoicescu, Jean-Charles Fabre, Matthieu Roy   +2 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Modeling and Performance Evaluation of Hybrid Classical–Quantum Serverless Computing Platforms

IEEE Transactions on Quantum Engineering
While quantum computing technologies are evolving toward achieving full maturity, hybrid algorithms, such as variational quantum computing, are already emerging as valid candidates to solve practical problems in fields, such as chemistry and operations ...
Claudio Cicconetti
doaj   +1 more source