Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Mental health monitoring in 5G Edge-Enabled Cognitive IoT with Temporal Shift Transformer and integrated Stackelberg Game Theory and Nomadic People Optimizer. [PDF]
Pavithra M, Ramya G.
europepmc +1 more source
Hybrid Intelligent System; A Self-Adaptive Network Protection System "Using Soft Computing and Open-Source Tools". [PDF]
Mohamed Hassan
openalex
Computing Large Deviations of First-Passage-Time Statistics in Open Quantum Systems: Two Methods [PDF]
Fei Liu, Jiayin Gu
openalex +1 more source
Prediction of Cloud Computing Resources Based on the Open Source Monitoring System
Кристина Кучерова
openalex +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Global 1-km Coastal Bathymetry from Sentinel-2 Wave Inversion using the Satellite-to-Shores (S2hores) Toolbox. [PDF]
Almar R +8 more
europepmc +1 more source
Testing SLURM open source batch system for a Tierl/Tier2 HEP computing facility
Giacinto Donvito +2 more
openalex +1 more source
A Closed System and an Open System in Energy Computation
openaire +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

