Results 191 to 200 of about 3,275,591 (372)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Bridging neuromorphic computing and deep learning for next-generation neural data interpretation. [PDF]
Front Comput NeurosciZhang M, Wang T, Zhu Z.
europepmc +1 more source
Nonlinearity of the Fidelity in Open Qudit Systems: Gate and Noise Dependence in High-dimensional Quantum Computing [PDF]
Jean-Gabriel Hartmann +4 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
GIEHP: A global, AI-powered platform for near real-time ecological intelligence. [PDF]
Environ Sci EcotechnolXu D, Wang YC.
europepmc +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Cloud-edge-device collaborative computing in smart agriculture: architectures, applications, and future perspectives. [PDF]
Front Plant SciYu P +5 more
europepmc +1 more source