Results 221 to 230 of about 3,275,591 (372)

Computing Large Deviations of First-Passage-Time Statistics in Open Quantum Systems: Two Methods [PDF]

Fei Liu, Jiayin Gu
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Data security storage and transmission framework for AI computing power platforms. [PDF]

Sci Rep
Chen J, Lu Z, Zheng H, Ren Z, Chen Y, Shang J.   +5 more
europepmc   +1 more source

SHERIFS: Open‐Source Code for Computing Earthquake Rates in Fault Systems and Constructing Hazard Models

, 2019
Thomas Chartier, Oona Scotti, H. Lyon‐Caen   +2 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Ten simple rules for building and maintaining sustainable high-performance computing infrastructure for research in resource-limited settings. [PDF]

PLoS Comput Biol
Galiwango R, Whalen CJ, Kebirungi G, Atwine MT, Kimera R, Ssekagiri A, Kimbowa TW, Lukyamuzi E, Nsubuga M, eLwazi ODSP, Ssentongo L, Mutegeki H, Fonner JM, Wuerthwein F, Berman A, Okalebo LB, McCarthy M, Kramer VS, Quinones M, Cruz P, Hurt D, Giovanni MY, Mulder N, Tartakovsky M, Kayondo J, Jjingo D.   +25 more
europepmc   +1 more source

PAD Cluster: An Open, Modular and Low Cost High Performance Computing System

, 1999
Volnys Borges Bernal, Sérgio Takeo Kofuji, Guilherme Matos Sipahi, Allan G. Anderson, Márcio Lobo Netto   +4 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Global 1-km Coastal Bathymetry from Sentinel-2 Wave Inversion using the Satellite-to-Shores (S2hores) Toolbox. [PDF]

Sci Data
Almar R, Bergsma EWJ, Thoumyre G, Giros A, Marchesiello P, Lemai-Chenevier S, Artigues S, Loyer S, Delvit JM.   +8 more
europepmc   +1 more source