Results 121 to 130 of about 4,329,795 (301)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modern Architecture for Contemporary Communities: Learning and Inclusion in the Open Work

open access: yes, 2021
According to the definition of ‘Open Work’ it is possible to reinterpret the experiences of Modern Movement in architecture through some eminent experimental model-schools that were able to define spaces for learning as places for communities, at the ...
Lino Cabras
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Deposition of Fine and Coarse Sand in an Open-Work Gravel Bed

open access: yes, 1984
The siltation of an experimental gravel bed, with three grades of sands moving in suspension and as bedload, was examined in a flume. For low suspended sediment concentrations (<300 mg∙L−1) the mean deposition rate was 1.34% of the initial gravel ...
Paul A. Carling
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The pillow hook : the pillow book as an "open work"

open access: yes
This paper is an attempt to unfold the many-layered text of Sei Shōnagon's Makura-no sōshi and to promote further the pleasure of its reading. On the one hand, the paper is based on Sei Shōnagon's major issue, that of wokashi, interpreted, following its
KRISTEVA, Tzvetana
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Activity-based working analyzed ::a disruptive new open work environment and its effects on a new product development organization

open access: yes, 2018
This paper offers a comparative study of workplace innovation looking at a new kind of open work environment referred as Activity-Based Working (ABW). Specifically for a state-of-the-art ABW work environment, we unveil distinct gains in team productivity,
Villarroel, Andrei
core  

Impact Mechanism and Effect Analysis of the Integration of Digital Economy and Real Economy on China’s Regional Low-Carbon Transitions

open access: yesSAGE Open
In the context of carbon peaking and carbon neutrality, this study addresses how the integration of digital economy and real economy (IDRE) influences regional low-carbon transitions (RLCT). Such exploration enhances the high-quality evolution of China’s
Yingjie Mi, Bing Zhou, Yufeng Li
doaj   +1 more source

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