Results 151 to 160 of about 4,329,795 (301)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
(A) STUDY ON THE OPEN WORK OF THE YI DYNASTY WHITE PORCELAIN
, 1984 現代는 機械文明의 發達로 모든 分野에 機械化, 自動化가 이루어져 가고 있으며, 따라서 대중이 사용하는 生活用品도 劃一化 되고 機械化에 발맞추어 形態의 單純化를 추구하는 경향이다. 그러나 한편으로는 機械化에 따른 副作用으로 生活의 餘裕가 없이 경직되어 숨을 쉴 틈조차 주어지지 않는다. 이런 상황 속에서, 本人은 옛 先人들의 陶磁器에 나타난 透刻紋을 통해 그들의 造形感覺 및 生活의 餘裕를 찾고자 했다. 本 硏究를 진행함에 있어서, 資料를 紋樣의 素材에
徐佑美.
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Prevalence of Work-Related Pain or Discomfort Among Urologists in the State of Florida: Results From the Florida Urologic Society Task Force on Ergonomic Challenges Experienced by Its Members. [PDF]
JMIR Hum FactorsDavid J +11 more
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Open work in comics: semiotic analysis and creation of object-comics
Comics present several starting points to multiple interpretations. In order to explore and amplify its possible meanings, we take inspiration in Umberto Eco’s reflections about the open work, a poetic message that stimulates its users to scroll through ...
Calvet, Lya Brasil
core +1 more source
Creating a smoother path to scientific publication. [PDF]
Mol OncolLemberger T, Ryan KM.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Listening, Consistency, and Our Role as a Journal. [PDF]
Plast Reconstr Surg Glob OpenJanis JE.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Navigating Precarious Paths: An Assessment of the Open Work Permit for Vulnerable Migrant Workers
Temporary migrant workers on closed work permits are vulnerable to exploitation and abuse. To address this, the Government of Canada introduced the Open Work Permit for Vulnerable Workers (OWP-V) in June 2019.
Weeks, Alyssa
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