Results 111 to 120 of about 489,146 (255)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Intelligent Systems with ApplicationsIntelligent forecasters are now being considered in the stock market, providing essential insights and strategic guidance to investors and traders by presenting analytical tools and predictive models, thus enabling informed decision-making and mitigating
Ashkan Safari +1 more
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Starting flow through nozzles with temporally variable exit diameter [PDF]
, 2005 Starting flow through a nozzle or orifice typically results in the transient formation of a leading vortex ring and trailing jet. Experiments are conducted to investigate the dynamics of this process in the case of a temporally variable nozzle exit ...
Dabiri, John O., Gharib, Morteza
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Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
A Refined Multi-Spring Model for Prestressed Precast Concrete Connections
BuildingsPrecast concrete with a moment-resisting frame with hybrid beam–column connections (HBC), which is featured by inelastic deformation induced by opening and closing of the interface between precast beam and column, has been emphasized in recent years ...
Hu Qi +3 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Construction and evaluation of a finger motor feedback system to improve finger dexterity
Frontiers in NeuroergonomicsIntroductionRecently, a link has been established between cognitive function and hand dexterity in older adults. Declines in cognitive function have been shown to impair performance in finger tapping movements.
Shingo Takahashi +4 more
doaj +1 more source
Assistive robotic device: evaluation of intelligent algorithms
, 2018 Assistive robotic devices can be used to help people with upper body disabilities gaining more autonomy in their daily life. Although basic motions such as positioning and orienting an assistive robot gripper in space allow performance of many tasks, it ...
Archambault, Philippe +4 more
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