Results 81 to 90 of about 489,146 (255)

Performance experiments with alternative advanced teleoperator control modes for a simulated solar maximum satellite repair [PDF]

Experiments are described which were conducted at the JPL Advanced Teleoperator Lab to demonstrate and evaluate the effectiveness of various teleoperator control modes in the performance of a simulated Solar Max Satellite Repair (SMSR) task. THe SMSR was
Bejczy, A. K., Das, H., Kim, W. S., Schenker, P. S., Zak, H.   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Effects of compressor speed and electronic expansion valve opening on the performance of R410a water chiller system

Wasit Journal of Engineering Sciences, 2020
Refrigeration and air conditioning systems consume high rates of electrical energy of the total global power consumption. The major part of this energy is used by compressor which is the main equipment in vapor compression refrigeration systems. In this
Ahmed H. Al-Hassani, Alaa R. Al-Badri
doaj   +1 more source

Computer simulation of platelet activation in a pulsatile ventricular assist device, through finite elements and a simplified geometry [PDF]

, 2017
Ventricular assist devices are a technological solution for patients who suffer from cardiac insufficiency and await a transplant. In this work, a new design of an implantable pulsatile blood pump is analyzed in terms of blood damage, by means of finite ...
Berli, Marcelo Eduardo, Campana, Diego Martin, Di Paolo, José, Fries, Exequiel, Ubal, Sebastian   +4 more
core  

Scallop swimming kinematics and muscle performance: modelling the effects of "within-animal" variation in temperature sensitivity [PDF]

, 2005
Escape behaviour was investigated in Queen scallops (Aequipecten opercularis) acclimated to 5, 10 or 15 degrees C and tested at their acclimation temperature.
Alexander RM, Anderson EJ, Bailey DM, Bailey DM, Beddow TA, Bennett AF, Cheng J-Y, Cheng J-Y, Cheng J-Y, Daniel TL, David M. Bailey, DeMont ME, Harper DG, Ian A. Johnston, Johnson TP, Johnson TP, Joll LM, Lu YT, Manuel JL, Marsh RL, Marsh RL, Marsh RL, Mellon D, Milward A, Morton B, Navas CA, Olson JM, Peck LS, Peplowski MM, Podolsky RD, Rome LC, Thorburn IW, Vogel S, Wakeling JM, Walker JA, Weihs D   +35 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Impact of ambidextrous leadership on innovative work behaviour and employee performance in the IT sector

Heliyon
The leadership role is crucial for motivating employees to do innovative work and discover new ideas and solutions. The IT sector is known for innovation.
Mahendiren Dinesh Babu, Kushwaha Bijay Prasad, Upadhyaya Tara Prasad   +2 more
doaj   +1 more source

"How May I Help You?": Modeling Twitter Customer Service Conversations Using Fine-Grained Dialogue Acts

, 2017
Given the increasing popularity of customer service dialogue on Twitter, analysis of conversation data is essential to understand trends in customer and agent behavior for the purpose of automating customer service interactions.
Austin J. L., Bird S., Bunt H., Core M. G., Gasic M., Kim S. N., Kim S. N., Klüwer T., Lafferty J. D., Mohammad S. M., Puterman M. L., Sacks H., Searle J. R.   +12 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source