Results 211 to 220 of about 4,540,854 (335)

Radical Ring-Opening Polymerization: Scope, Limitations, and Application to (Bio)Degradable Materials.

Chemical Reviews, 2017
Antoine Tardy, J. Nicolas, D. Gigmes, Catherine Lefay, Yohann Guillaneuf   +4 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Bandgap opening in few-layered monoclinic MoTe2

Nature Physics, 2015
D. Keum, Suyeon Cho, Jung Ho Kim, Duk-Hyun Choe, Ha-Jun Sung, Min Kan, Haeyong Kang, Jae-Yeol Hwang, Sung Wng Kim, Heejun Yang, K. Chang, Young Hee Lee   +11 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The telovelar approach reshaped: a new perspective from inside the fourth ventricle. [PDF]

Childs Nerv Syst
Longatti P, Fiorindi A, Siddi F, Boaro A, Canova G, Feletti A.   +5 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Interobserver Reproducibility of the Visual Echocardiographic Scoring System for Left Ventricular Filling Pressure. [PDF]

Cureus
Uruma Y, Murayama M, Uemura W, Sakai N, Shimomura M, Nozaki K, Kunieda Y.   +6 more
europepmc   +1 more source

Femtosecond x-ray spectroscopy of an electrocyclic ring-opening reaction

Science, 2017
Andrew R. Attar, Andrew R. Attar, Aditi Bhattacherjee, Aditi Bhattacherjee, C. D. Pemmaraju, C. D. Pemmaraju, K. Schnorr, K. Schnorr, K. D. Closser, D. Prendergast, Stephen R. Leone, Stephen R. Leone   +11 more
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Pharyngeal High-Resolution Manometry-Based Evaluation of Dysphagia Recovery After Lateral Medullary Syndrome: A Case Series of Two Patients. [PDF]

Clin Case Rep
Yoshida H, Shibata S, Inamoto Y, Fukushima R, Wada Y, Otaka Y.   +5 more
europepmc   +1 more source