Results 281 to 290 of about 4,577,170 (346)

Interobserver Reproducibility of the Visual Echocardiographic Scoring System for Left Ventricular Filling Pressure. [PDF]

Cureus
Uruma Y, Murayama M, Uemura W, Sakai N, Shimomura M, Nozaki K, Kunieda Y.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Speculum-Induced Intraocular Pressure Elevation During Cataract Surgery and Its Association with Axial Length: A Retrospective Clinical Study. [PDF]

J Clin Med
Suzuki H.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The telovelar approach reshaped: a new perspective from inside the fourth ventricle. [PDF]

Childs Nerv Syst
Longatti P, Fiorindi A, Siddi F, Boaro A, Canova G, Feletti A.   +5 more
europepmc   +1 more source

Open, open, open tudo: ciência aberta

, 2017
openaire   +1 more source

Quantitative Assessment of Masticatory Function in Patients with Temporomandibular Joint Arthralgia: A Pilot Clinical Study. [PDF]

J Clin Med
Vogt V, Dahlmeier L, Colombo V, Kaldas M, Özcan M, Zumbrunn Wojczyńska A.   +5 more
europepmc   +1 more source

Clinical efficacy and failure-related factors of the loose-seton procedure combined with transanal opening of the intersphincteric space technique (LoSet-TROPlS) in the treatment of complex anal fistulas. [PDF]

Tech Coloproctol
Ma Q, Dong M, Hua H, Wang Z, Wu J, Wu J, Jin L.   +6 more
europepmc   +1 more source

Dragonfly-Wing-Inspired Bluff-Body Piezoelectric Harvester for Efficient Low-Wind-Speed Energy Harvesting. [PDF]

Micromachines (Basel)
Zhou Z, Shang X, Xia Y, Zhu P.
europepmc   +1 more source

Evaluation of shunt valve flow dynamics in series. [PDF]

Fluids Barriers CNS
Williams GLM, Thompson K, Meggyesy M, Biswas D, Lee R, Chandan Reddy S, Maroufi SF, Harris CA, Luciano M.   +8 more
europepmc   +1 more source