Results 141 to 150 of about 1,422,266 (292)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Opening Statement

The Forestry Chronicle, 1986
  +4 more sources

Adult-Onset Effmann Type IIA2 Y-Type Urethral Duplication Presenting as Unexplained Perineal Wetness: A Case Report Highlighting Diagnostic Pitfalls and Tailored Surgical Management. [PDF]

IJU Case Rep
Ueda N, Kimura T, Takezawa K, Kato T, Hatano K, Kakuta Y, Nonomura N, Kawashima A.   +7 more
europepmc   +1 more source

Press statement: Opening of Sorrento Motel [PDF]

, 2014

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Endoscopic membranectomy for a 2-day-old neonate with duodenal membranous atresia: the youngest case reported. [PDF]

Endoscopy
Guo D, Wang L, Cao L, Xiong H, Huang W, Fang X, He X.   +6 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Congenital syngnathia: a case report of osseous fusion between the maxilla and mandible. [PDF]

Front Pediatr
Wang H, Zhang L, Li J.
europepmc   +1 more source

Press statement - Opening of Charles Parsons (SA) [PDF]

, 2014

core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source