Results 191 to 200 of about 96,333 (266)

Crisis support teams' technological openness and learning attitudes toward the AI based virtual patient system <i>crisis support VR</i>. [PDF]

Front Digit Health
Mårtensson SK, Hveem C, Lamb M, Knez R.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Convergent thinking, divergent thinking, and openness to experience as predictors of academic success among high-achieving and typical-achieving medical students. [PDF]

BMC Med Educ
Abdulla Alabbasi AM, Alansari AM, Deifalla A, Runco MA, Sequeira RP, Alotaibi GA, AlSaleh A.   +6 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Examining the utility of process-focused data driven psychological networks for individualizing psychological treatment in chronic pain-A single case experiment testing the centrality hypothesis. [PDF]

Front Psychol
Lavefjord A, Sundström FTA, Preihs L, Hammar A, Forslund S, Clason van de Leur J, Scholten S, Buhrman M, McCracken LM.   +8 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Development and Internal Validation of a Predictive Model of Perceived Stress Among Military Students: A LASSO Regression Analysis. [PDF]

Int J Environ Res Public Health
Al-Mahrouqi T, Al Alawi M, Al Harrasi A, Al Zadjali M, Al Jahwari A, Al Shamli S, Al Housni A.   +6 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An associative model of Chinese university teachers' personality traits and students' classroom engagement from the teacher's perspective: the mediating role of emotional regulation. [PDF]

Front Psychol
Lu B, Hou W, Sun J, Wang L.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source