Results 221 to 230 of about 1,531,725 (338)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A Crowdsourced Open-Source Kazakh Speech Corpus and Initial Speech\n Recognition Baseline [PDF]

, 2020
Yerbolat Khassanov, Saida Mussakhojayeva, Almas Mirzakhmetov, Alen Adiyev, Mukhamet Nurpeiissov, Hüseyin Atakan Varol   +5 more
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Infrastrukturen, Kulturwandel und Nachhaltigkeit – eine Open Policy für das Austrian Centre for Digital Humanities der Österreichischen Akademie der Wissenschaften

Library Ideas, 2019
Vanessa Hannesschläger, Redaktion Libreas   +1 more
doaj   +1 more source

Flipped learning, personality traits, and student outcomes: evidence from a controlled university trial. [PDF]

Front Psychol
Dabaj T, İşman A.
europepmc   +1 more source

Four Lectures on Analytic Solutions in Open String Field Theory

, 2019
Theodore Erler
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Heterogeneous associations of health expenditure, environmental pollution, and economic growth on life expectancy in BRICS economies. [PDF]

Front Public Health
Ridwan M, Antor ZA, Akther A, Ko J, Fakher HA, Leung CK, Ming WK.   +6 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The relationship between medical students' attitudes toward artificial intelligence and their personality traits: a multicenter study in China. [PDF]

Front Public Health
Qi J, Zeng Y, Wang H, Xiang Y, Fang Z, Zhang Y, Bao T, Yan S, Liu L, Su Y, Jiang X, Chen S.   +11 more
europepmc   +1 more source