Results 161 to 170 of about 3,262,531 (384)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

EXPERIENCES USING THE PUMP-OXYGENATOR FOR OPEN CARDIAC SURGERY IN MAN [PDF]

open access: bronze, 1957
David Mendelsohn   +4 more
openalex   +1 more source

An experiment in online AT open innovation

open access: yes, 2011
Objective. To initiate an experiment to see if an online tool can facilitate creation of new Assistive Technology (AT) through open innovation that engages the public (primarily end users and carers), prescribers, innovators and manufacturers. The final results and conclusions of the funded project which focus on AT relevant to access and use of ...
Draffan, E.A.   +4 more
openaire   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

„OPEN FOR CONSERVATION”: LIVE EXPERIENCES

open access: yesProtection of Cultural Heritage, 2019
The need to show to the public issues related to conservation of cultural properties first became clear in the eighties during the great projects conducted in the Roman forum. Three major conservation innovations were introduced at that time: documentation became part of the contract specifications; consolidation was performed using slaked lime; the ...
openaire   +4 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Personality traits and body mass index in a Korean population.

open access: yesPLoS ONE, 2014
BackgroundOverweight and obesity is a serious problem worldwide related to cardiovascular and other diseases. Personality traits are associated with the abnormal body mass indices (BMIs) indicative of overweight and obesity.
Unjin Shim   +7 more
doaj   +1 more source

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