Results 131 to 140 of about 57,264 (259)

The Role of Genetically Distinct Central Amygdala Neurons in Appetitive and Aversive Responding Assayed with a Novel Dual Valence Operant Conditioning Paradigm. [PDF]

eNeuro, 2023
Dorofeikova M, Stelly CE, Duong A, Basavanhalli S, Bean E, Weissmuller K, Sifnugel N, Resendez A, Corey DM, Tasker JG, Fadok JP.   +10 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The role of the GABAergic cells of the median raphe region in reinforcement-based learning

Scientific Reports
Learning and memory are important in everyday life as well as in pathological conditions. The median raphe region (MRR) contributes to memory formation; however, its precise role and the neurotransmitters involved have yet to be elucidated.
Tiago Chaves, Bibiána Török, Csilla Fazekas, Pedro Correia, Peter Karailiev, Henrieta Oravcova, Eszter Sipos, László Biró, József Haller, Daniela Jezova, Dóra Zelena   +10 more
doaj   +1 more source

The Evoked Potential Operant Conditioning System (EPOCS): A Research Tool and an Emerging Therapy for Chronic Neuromuscular Disorders. [PDF]

J Vis Exp, 2022
Hill NJ, Gupta D, Eftekhar A, Brangaccio JA, Norton JJS, McLeod M, Fake T, Wolpaw JR, Thompson AK.   +8 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Specific Plasticity Loci and Their Synergism Mediate Operant Conditioning. [PDF]

J Neurosci, 2022
Momohara Y, Neveu CL, Chen HM, Baxter DA, Byrne JH.   +4 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Automated Operant Conditioning Devices for Fish. Do They Work? [PDF]

Animals (Basel), 2021
Gatto E, Santacà M, Verza I, Dadda M, Bisazza A.   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Zebrafish excel in number discrimination under an operant conditioning paradigm. [PDF]

Anim Cogn, 2022
Bisazza A, Santacà M.
europepmc   +1 more source