Results 111 to 120 of about 6,171,784 (375)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Coarse and Fine Two-stage Fast Adjustment of the Ring Platform for Reactor Coolant Pump Bolt Detection based on Decoupling Parallel Mechanism

Jixie chuandong, 2021
The ring platform serves as the movement and operating benchmark for the online inspection of the nuclear reactor coolant pump bolts，its rapid and high-precision adjustment is the key to whether the bolt online inspection can proceed successfully. Aiming
Shisen Lin, Lubin Hang, Baojun Zhang, Lusheng Zhou, Xiaobo Huang, Junrong Chen, Ziyu Liu, Pengcheng Zhang   +7 more
doaj  

A Phase Noise Reduction Technique in LC Cross-coupled Oscillators with Adjusting Transistors Operating Regions [PDF]

, 2020
R. Aghabagheri, Hossein Miar Naimi, Mohsen Javadi   +2 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Keynesian Dynamics and the Wage-Price Spiral:Estimating and Analyzing a Baseline Disequilibrium Approach [PDF]

In this paper, we reformulate the theoretical baseline DAS-AD model of Asada, Chen, Chiarella and Flaschel (2004) to allow for its somewhat simplified empirical estimation.
C. Chiarella, P. Chen, W. Semmler
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Emotional, Social and Occupational Adjustment among Oncology Nurses

International Journal of Hematology-Oncology and Stem Cell Research, 2016
Background: Social, occupational and emotional adjustment of Oncology nurses were assessed and compared with other nurses in this study. Subjects and Methods: One hundred nurses including Oncology nurses (n=50) and non-Oncology nurses (n=50) participated
Mohammad Vaezi, Mahboubeh Vala, Maryam Souri, Ashraf Mousavi, Ardeshir Ghavamzadeh   +4 more
doaj  

Numerical parametric study of a Kaplan turbine incorporated with a sub runner considering analysis of hydraulic dissipation

Results in Engineering
In this paper, a novel approach on Kaplan turbines, proposed and published in a US patent, has been investigated numerically using CFD tool. This approach includes the incorporation of an extra runner, called sub runner, into the main runner of a typical
Amirhossein Khoddami, Mojtaba Tahani, Fathollah Pourfayaz, Alireza Riasi, Khalil Allah Sajadian   +4 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Urban Transport Market Theoretical Analysis. [PDF]

, 1993
1.The Institute for Transport Studies (ITS) was commissioned by the Department of Transport (DoT), the Association of Metropolitan Authorities (AMA) and the Passenger Transport Executive Group (PTEG) to undertake this project in November 1992.
Nash, C.A., Preston, J.M., Toner, J.P.
core