Results 111 to 120 of about 719,305 (325)

Effect of an Adjustable Hinged Carbon Fiber Operating Table on Sagittal Alignment of the Lumbar Spine [PDF]

open access: gold, 2022
Masato Tanaka   +9 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Generalization of multi-level modeling methods for development and analysis of operating conditions of large heat supply systems★

open access: yesE3S Web of Conferences, 2018
The paper presents a methodology of multi-level modeling of thermal-hydraulic conditions of large heat supply systems on the basis of the scientific area of research – the theory of hydraulic circuits – that has been developed at MESI SB RAS.
Shalaginova Zoya. I.   +1 more
doaj   +1 more source

Productivity and farm size in Australian agriculture: reinvestigating the returns to scale [PDF]

open access: yes
Higher productivity among large farms is often assumed to be a result of increasing returns to scale. However, using farm-level data for the Australian broadacre industry, it was found that constant or mildly decreasing returns to scale is more typical ...
Nossal, Katarina, Sheng, Yu, Zhao, Shiji
core   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

Farm Sector Capital Structure Indicators in Estonia [PDF]

open access: yes
Empirical tests are provided to determine the optimal leverage adjustment in transitional economy. Econometric model of agricultural firm capital structure is specified and estimated in order to analyze, how different factors affect agricultural firm's ...
Huirne, Ruud B.M.   +2 more
core   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

Deployable reflector antenna performance optimization using automated surface correction and array-feed compensation [PDF]

open access: yes
Methods for increasing the electromagnetic (EM) performance of reflectors with rough surfaces were tested and evaluated. First, one quadrant of the 15-meter hoop-column antenna was retrofitted with computer-driven and controlled motors to allow automated
Bailey, M. C.   +2 more
core   +1 more source

Municipal Bankruptcy Under the 1976 Amendments to Chapter IX of the Bankruptcy Act [PDF]

open access: yes, 1976
This articles examines the new Chapter IX of the Bankruptcy Act, particularly its effectiveness in providing insolvent or financially distressed municipalities with a simpler and more efficient method of obtaining financial relief. The articles discusses
Bond, Kenneth W.
core   +1 more source

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