The DURATIONS randomised trial design: Estimation targets, analysis methods and operating characteristics. [PDF]
Background: Designing trials to reduce treatment duration is important in several therapeutic areas, including tuberculosis and bacterial infections. We recently proposed a new randomised trial design to overcome some of the limitations of standard two ...
Quartagno M +4 more
europepmc +3 more sources
Operating characteristics of the rank-based inverse normal transformation for quantitative trait analysis in genome-wide association studies. [PDF]
Quantitative traits analyzed in Genome-Wide Association Studies (GWAS) are often non-normally distributed. For such traits, association tests based on standard linear regression are subject to reduced power and inflated type I error in finite samples ...
McCaw ZR +4 more
europepmc +2 more sources
Neyman-Pearson classification algorithms and NP receiver operating characteristics. [PDF]
An umbrella algorithm and a graphical tool for asymmetric error control in binary classification. In many binary classification applications, such as disease diagnosis and spam detection, practitioners commonly face the need to limit type I error (that ...
Tong X, Feng Y, Li JJ.
europepmc +3 more sources
The R package gsbDesign provides functions to evaluate the operating characteristics of Bayesian group sequential clinical trial designs. More specifically, we consider clinical trials with interim analyses, which compare a treatment with a control, and ...
Florian Gerber, Thomas Gsponer
doaj +2 more sources
The ROC Toolbox: A toolbox for analyzing receiver-operating characteristics derived from confidence ratings. [PDF]
Koen JD +3 more
europepmc +2 more sources
Dimension of model parameter space and operating characteristics in adaptive dose-finding studies. [PDF]
Iasonos A +5 more
europepmc +2 more sources
Combining low-dimensional layers of dissimilar metal oxide materials to form a heterojunction structure offers a potent strategy to improve the performance and stability of thin-film transistors (TFTs).
Wejdan S. AlGhamdi +8 more
semanticscholar +1 more source
Review of the Development of Science and Technology of Cereals, Oils and Foods in the Past 30 Years
Cultural inheritance is the spiritual genealogy and life source to sustainable development for a journal. This paper took Science and Technology of Cereals, Oils and Foods (in brief “this journal”) as an example to review.
LI Si-yuan, TAN Hong-zhuo, YOU Meng-chen
doaj +1 more source
Applying Meta-Analytic-Predictive Priors with the R Bayesian Evidence Synthesis Tools
Use of historical data in clinical trial design and analysis has shown various advantages such as reduction of number of subjects and increase of study power. The metaanalytic-predictive (MAP) approach accounts with a hierarchical model for between-trial
Sebastian Weber +4 more
doaj +1 more source
Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain. [PDF]
Kroenke K +4 more
europepmc +2 more sources

