Results 51 to 60 of about 416,894 (288)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

THE EFFECT OF OPERATING LEVERAGE AND OPERATING PROFIT MARGIN TOWARDS INCOME SMOOTHING PRACTICES (AN EMPIRICAL STUDY ON MANUFACTURING COMPANIES LISTED ON INDONESIA STOCK EXCHANGE YEAR 2014-2016) [PDF]

open access: yes, 2017
The purpose of this research is to examine the influence of operating leverage and operating profit margin toward the practice of income smoothing.
Fata Imanda
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

PENGARUH LEVERAGE DAN RASIO LIKUIDITAS TERHADAP EARNING PER SHARE (Studi Pada Perusahaan Yang Tergabung Dalam Indeks LQ45) [PDF]

open access: yes, 2009
Title : "Influence Leverage And Liquidity Ratio To Earning Per Share (Study At Company Merged Into By Index LQ45)". (Ekoadi Purwono, Drs. Dhaniel Syam MM, Ak, Dra. Siti Zubaidah MM, Ak).
PURWONO, EKOADI
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

PENGARUH STRUKTUR ASSET DAN OPERATING LEVERAGE TERHADAP STRUKTUR MODAL PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA PADA PERIODE 2012-2013 [PDF]

open access: yes, 2015
SITI MAYSAROH. The Influence of Assets Structure and Operating Leverage to Capital Structure on Listed Companies in Indonesian Stock Exchange in 20122013. Skripsi.
MAYSAROH, SITI
core  

Snow and leverage [PDF]

open access: yes, 2010
Using a sample of highly (over-)leveraged Austrian ski hotels undergoing debt restructurings, we show that reducing a debt overhang leads to a significant improvement in operating performance (return on assets, net profit margin).
Giroud, Xavier   +3 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Pengaruh Ukuran Perusahaan, Operating Leverage dan Dividen Payout Ratio Terhadap Beta Saham Pada Perusahaan Manufaktur yang Terdaftar di BEI Periode 2009 - 2011 [PDF]

open access: yes, 2013
WAHYU SETYA RAHARJO, 2013; Effect of Company Size, Operating Leverage and Dividend Payout Ratio Beta Stocks in Manufacturing Companies Listed in Indonesia Stock Exchange Year 2009-2011, led by Yunika Murdayanti, SE, M.Si, M.Ak. as lecturer I dan Diena
RAHARJO, WAHYU SETYA
core   +1 more source

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