Results 91 to 100 of about 1,950,867 (244)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Evaluating the Role of Magnification in Minimising Tooth Substance Loss During Endodontic Access Cavity Preparation: An In Vitro Volumetric Analysis Using CBCT and IOS

open access: yesMedicina
Background and Objectives: The aim of this study was to evaluate the volume of dental tissue removed during conventional versus microscope-assisted coronal access cavity preparation by an undergraduate student in extracted mandibular incisors, and to ...
Rafaela Martins   +3 more
doaj   +1 more source

Light sheet adaptive optics microscope for 3D live imaging [PDF]

open access: yes, 2013
Optical microscopy is still the main research tool for many biological studies. Indeed with the advent of genetic manipulation and specifically, the use of fluorescent protein expressing in animals and plants it has actually seen a renaissance in the ...
BOURGENOT, CYRIL,JULES,TUGDUAL
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

The dental-operating microscope and its slow acceptance.

open access: yes, 2002
This article presents a review of the history of the dental-operating microscope and how it experienced slow acceptance. Following its introduction in 1982, it wasn\u27t until 1997 that microscopy training became manditory for Advanced Specialty ...
Selden, Howard S, Selden, Howard S, DDS
core   +2 more sources

An Operating Microscope-Assisted Therapy For Type II Dens Invaginatus

open access: yesInternational Dental Journal
Introduction: Dens invaginatus is a developmental anomaly resulting from the invagination of the enamel organ into the dental papilla during odontogenesis, driven by multiple etiological factors.
Yuanpei He
doaj   +1 more source

Microscopiok: Nature under the microscope

open access: yes, 2022
A few years ago, I was gifted a microscope. For a long time, it has been locked in a cupboard, sealed inside its case. Then , I started using it and became passionate about this instrument: I discovered that there is another world around us, a magical ...
rosella cristiani, priscilla farina
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

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