Results 121 to 130 of about 2,887,710 (306)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Effect of Surgical Specimen Chain Management Information System on specimen management in operating room: a pilot Quasi-Experimental study

BMC Nursing
Background The proper handling of surgical specimen during the pre-analytical phase directly impacts diagnostic accuracy and patient’s treatment plan. Specimen handling involves multiple steps and departments, making it prone to errors. Ensuring seamless
Xu Zhang, Xiaofen Yu, Mengtian Wang, Feiyan Shen, Jing Shen, Chunju Yang, Min Hong   +6 more
doaj   +1 more source

Operating Room Nurse Burnout: A Global Challenge With SDG Solutions

Building a support network, sharing best practices, and crafting collective solutions can pave the way for reducing burnout rates and improving health care.
Kalivani, Poongawanam *
core  

Factors compromising safety in surgery: stressful events in the operating room

, 2010
Background Stressful events occur in the operating room (OR) with potentially severe consequences for patient safety. We recorded the incidence of these events in the OR, assessed the levels of stress that they caused, and investigated their ...
Arora, S., Darzi, A., Nestel, D., Tierney, T., Hull, L., Woloshynowych, M., Kneebone, R.   +6 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Knowledge, attitudes, and practices of family members of children aged 2–6 years with snoring regarding pediatric snoring and its management

BMC Public Health
Background This study aimed to explore the knowledge, attitudes, and practices (KAP) of family members of children aged 2–6 years who snore, particularly regarding prevention, treatment, and care. Methods Conducted in Shenzhen from July 20 to October 20,
Zhenghan Fang, Yanxia Zhao
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Enhancing geriatric perioperative care competencies through structured, geriatric-focused clinical rounds for operating room nursing students: a quasi-experimental study

BMC Nursing
Background The growing number of older adults undergoing surgery highlights the need for strengthened geriatric competencies among operating room (OR) nursing students.
Leila Sadati, Sahar karami, Nasser Hassaninia, Farimah Shahraki   +3 more
doaj   +1 more source

Exploring Determinants of Turnover Intention Among Operating Room Nurses: a Systematic Review

openQuesta revisione sistematica mira a investigare i fattori che influenzano l'intenzione di turnover tra gli infermieri di sala operatoria (SO) e a determinare la prevalenza di questo fenomeno a livello globale. Background: Il turnover degli infermieri,
LEONE, SEBASTIANA
core