Results 171 to 180 of about 278,023 (341)

Pharmacokinetic and Bioequivalence Evaluation of Two Sitagliptin Tablets With Different Salts in Healthy Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract The objective of the current study was to evaluate the rate and extent of absorption of a test formulation (sitagliptin hydrochloride) and a reference formulation (sitagliptin phosphate). An open‐label, randomized, single‐dose, single‐center, 2‐sequence, 2‐period, and cross‐over phase 1 study was implemented to assess the pharmacokinetic ...
Usok Hyun   +7 more
wiley   +1 more source

The accuracy of the risk assessment scale for pressure ulcers in adult surgical patients: a network meta-analysis

open access: yesBMC Surgery
Background This study aims to synthesize existing evidence regarding the accuracy of different scales to assess the risk of intraoperative acquired pressure injury (IAPI), thus providing guidance for the accurate clinical screening of IAPI risk and ...
Yanfen Shang   +6 more
doaj   +1 more source

Phenobarbital Bioequivalence in Chinese Population: Considering the Role of Food on Pharmacokinetics

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Epilepsy is one of the most severe neurological disorders in the world, which might seriously endanger the lives of patients. Phenobarbital is an important medicine clinically used for the treatment of epilepsy, and it is irreplaceable in the treatment of generalized tonic–clonic seizures, focal seizures, status epilepticus, and pediatric ...
Wang Xinman   +3 more
wiley   +1 more source

Secondary schools' preparation for roll‐out of Curriculum for Wales: Case studies of approaches to health and well‐being in the context of national education system reform

open access: yesThe Curriculum Journal, EarlyView.
Abstract Schools are increasingly positioned as key settings for promoting health behaviours and well‐being. Curriculum for Wales (CfW) represents major national reform of the Welsh education system, placing unprecedented focus on health and well‐being for learners in compulsory education (aged 3–16).
Rochelle Embling   +3 more
wiley   +1 more source

Barnes Hospital Record [PDF]

open access: yes, 1952
https://digitalcommons.wustl.edu/bjc_barnes_record/1061/thumbnail ...

core   +1 more source

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients

open access: yesDrug Testing and Analysis, EarlyView.
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke   +4 more
wiley   +1 more source

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