Results 61 to 70 of about 58,789 (307)

Visualizing the demand for various resources as a function of the master surgery schedule: A case study. [PDF]

open access: yes
This paper presents a software system that visualizes the impact of the master surgery schedule on the demand for various resources throughout the rest of the hospital.
Belien, Jeroen   +2 more
core   +2 more sources

CONTENT ANALYSIS OF OBSERVATION AND PRACTICE CONSIDERING EFFECTS OF LEARNING IN PERIOPERATIVE NURSING CARE [PDF]

open access: yes, 2000
The aim of this study is to clarify the contents of understanding of students in two activities; that is, observation of operating rooms executed in the second grade a a part of the class of perioperative nursing care, and the practice of entering the ...
TAKAYANAGI, Tomoko   +5 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Effect of flumazenil on recovery of memory following recovery of consciousness from general anesthesia with remimazolam: a randomized, open-label, single-center controlled trial

open access: yesJA Clinical Reports
Background Recovery of consciousness from general anesthesia with remimazolam, an ultrashort-acting benzodiazepine, occurs rapidly. However, patients after recovery of consciousness from general anesthesia with remimazolam often experience periods of ...
Keiko Nobukuni   +8 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Innovative Ventilation Technology for Operating Rooms

open access: yesCurrent Directions in Biomedical Engineering, 2018
The purpose of this work was to evaluate the decontamination potential of the Potok system both in an experimental setting in a research Operating Room (OR) with standalone Air Decontamination Units (Potok 150-M-01) and in a clinical setting in a real ...
Gruber Sabine   +2 more
doaj   +2 more sources

Tailoring Information for Operating Rooms [PDF]

open access: yes, 2017
This project investigates what and how information should be delivered to staff in hospital operating rooms. I have designed a holistic platform for critical in-operation information. I have worked in operating rooms observing heart procedures, which are
Agerup, Rasmus
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Operating room planning and scheduling: A literature review. [PDF]

open access: yes
This paper provides a review of recent research on operating room planning and scheduling. We evaluate the literature on multiple fields that are related to either the problem setting (e.g.
Belien, Jeroen   +2 more
core  

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